Determine Factors Affecting AAV Capsid Uncoating Using AFM Nano-indentation
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Stability of Norwalk Virus Capsid Protein Interfaces Evaluated by in Silico Nanoindentation
Norwalk virus causes severe gastroenteritis for which there is currently no specific anti-viral therapy. A stage of the infection process is uncoating of the protein capsid to expose the viral genome and allow for viral replication. A mechanical characterization of the Norwalk virus may provide important information relating to the mechanism of uncoating. The mechanical strength of the Norwalk ...
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تاریخ انتشار 2012